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Stem Cell Research

Maintaining pluripotency in mouse embryonic stem cells

15 years, 3 months ago

1286  0
Posted on Aug 28, 2003, 1 p.m. By Bill Freeman

Researchers supported by Japanese funds recently identified a gene specifically expressed in mouse embryonic stem cells and preimplantation embryos. They provide evidence that the product of this gene, called nanog, is a homeobox transcription factor that plays a role in preventing differentiation and is critical to maintaining pluripotency in mouse embryonic stem cells.

Researchers supported by Japanese funds recently identified a gene specifically expressed in mouse embryonic stem cells and preimplantation embryos. They provide evidence that the product of this gene, called nanog, is a homeobox transcription factor that plays a role in preventing differentiation and is critical to maintaining pluripotency in mouse embryonic stem cells.
(Mitsui et al., Cell 113:631&endash;642, 2003)

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