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Alternative Medicine A4M Anti-Aging Anti-Aging Botanical Agents

Evolution of Herbal Cures for Cancer: Molecular Science Holds the Key

1 year, 10 months ago

7690  0
Posted on Oct 02, 2019, 12 p.m.

Article courtesy of: Kenneth Kwok, Co-President of the Asian World Anti-Aging And Well-Being Association.

Current State 


The worlds of conventional and regenerative medicine are increasingly adopting the practice of herbal remedies, also known as botanical medicine, which have been used in many traditional medicine systems throughout centuries. 

Herbal remedies are produced from all parts of a plant including the roots, leaves, berries and flowers; these may contain active ingredients that can cause chemical changes in the body. Typically herbal remedies can be either applied to the skin to treat disease or taken by mouth to treat disease and promote health; herbs and plants are sometimes categorized as biological treatments.

The Next Quantum Leap in Herbal Cures


In the research towards holistic preventative health, anti-aging hallmarks such as stem cell exhaustion, mitochondrial dysfunction, senescent cells  accumulation and telomere attrition are being researched with the latest advances in molecular biology at the DNA sequencing level. 

Plant genomic DNA extraction and sequencing has been carried out for many herbs with proven medicinal qualities, such as Boehmeria nivea, Impatiens balsamina, Ficus deltoidea, Centella asiatica and Andrographis paniculata. This molecular technique is another highly reliable alternative for plant species identification besides phytochemical profiling, with the aim of pinpointing at 99.0% and higher accuracy cure-oriented programs for cancer and other life threatening diseases. For now, the focus is on complementary and supportive uses alongside surgery, radiation therapy, chemotherapy, immunotherapy, targeted therapy, hormone therapy, stem cell transplant, precision medicine and other conventional methods of treating cancer. 


Proliferation of DNA and genetic based identification 


Appropriate use of genetic methods for botanical identification is based on the type of sequencing used as well as testing region selection. Materials that are unknown, fresh, or lightly processed are best tested through the use of long, universal deoxyribonucleic acid (DNA) regions (e.g., DNA barcodes). 

Well-known genome sequencing research foundations supported by Illumina, BGI Genomics and Forall Biotech focus on DNA extraction techniques that address the presence of inhibitory compounds, which often occur in abundance within herbs and spices. Identification accuracy is improved when comparing genetic data of any type with a reference database that contains expertly determined vouchered materials, a variety of closely related species, and multiple specimens of the same species.


Benefits of Herbal Cures


Many scientific studies have examined the effects of various herbs on people with cancer, and some remedies have been shown to reduce side effects of cancer treatment; certain plant extracts have even been found to have anti-cancer effects and have been turned into chemotherapy-based, alternative medicine oriented or other supplementary cancer-curing and supporting programs. These include vincristine from the periwinkle plant, polyphenols from the boehmeria nivea root and taxanes from the bark of the Pacific yew tree.

At consultation with medical practitioners, mainstream and well respected practices in alternative medicine such as acupuncture, traditional Chinese medicine, homeopathy, Ayurveda, biofeedback, nutritional therapy and tai chi / Qi gong etc can be incorporated for holistic healing health. 


Side effects of Herbal Cures


Certain herbs may interact with conventional cancer treatment or medicines, and change how the treatment works or the dose is absorbed. Herbs taken in large quantities can be toxic, and this is where any herb based product must complete the standard tests of non-toxicity, heavy metals and pesticides. Some companies such as Nutraceutical Corporation, Forall Biotech and Rainbow Light take it to an even higher level, by leveraging on genomics, natural and molecular science and offer non-chemical and non-pharma solutions. 


The million dollar question: Is there an herbal cure for cancer?


Historically speaking, there has been a lack of scientific research and evidence herbal remedies alone can cure or treat cancer.

Molecular science and its recent advances have significantly changed this landscape. Breakthroughs are being achieved on a monthly basis by revisiting decades worth of data collection and research works through genomics principles, and subsequently entering into new FDA-regulated clinical trials. Promising results are particularly seen in the areas such as EMT-MET reversal. 

Specifically, the epithelial–mesenchymal transition (EMT) is a process by which epithelial cells lose their cell polarity and cell-cell adhesion, and gain migratory and invasive properties to become mesenchymal stem cells; these are multipotent stromal cells that can differentiate into a variety of cell types. Epithelial–mesenchymal transition is essential for numerous developmental processes including mesoderm formation and neural tube formation, and has also been shown to occur in wound healing, in organ fibrosis and in the initiation of metastasis in cancer progression. On the other hand, MET is the reverse process of epithelial–mesenchymal transition (EMT). Recent studies involving herbs such as boehmeria nivea demonstrate that this can be achieved, which essentially reverts previously cancerous cells into healthy ones. 


Looking Forward 


We continue to await with excitement for new sustainable ways in improving the overall healthcare system of the world, first in the field of preventive medicine followed by regenerative medicine. In combination, it should contribute towards prolonging a healthy lifespan and preventing the onset of cancer. 

Article courtesy of:

Kenneth Kwok


Asian World Anti-Aging And Well-Being Association


Materials provided by:

Note: Content may be edited for style and length.

This article is not intended to provide medical diagnosis, advice, treatment, or endorsement.



  1. Gerber B, Müller H, Reimer T, Krause A, Friese K. Nutrition and lifestyle factors on the risk of developing breast cancer. Breast Cancer Research and Treatment. 2003;79(2):265–276. 
  2. Shun MC, Yu W, Gapor A, et al. Pro-apoptotic mechanisms of action of a novel vitamin E analog (α-TEA) and a naturally occurring form of vitamin E (δ-Tocotrienol) in MDA-MB-435 human breast cancer cells. Nutrition and Cancer. 2004;48(1):95–105. 
  3. Wang XF, Witting PK, Salvatore BA, Neuzil J. Vitamin E analogs trigger apoptosis in HER2/erbB2-overexpressing breast cancer cells by signaling via the mitochondrial pathway. Biochemical and Biophysical Research Communications. 2005;326(2):282–289. 
  4. Gerber B, Scholz C, Reimer T, Briese V, Janni W. Complementary and alternative therapeutic approaches in patients with early breast cancer: a systematic review. Breast Cancer Research and Treatment. 2006;95(3):199–209. 
  5. Lesperance ML, Olivotto IA, Forde N, et al. Mega-dose vitamins and minerals in the treatment of non-metastatic breast cancer: an historical cohort study. Breast Cancer Research and Treatment. 2002;76(2):137–143. 6. Saintot M, Mathieu-Daude H, Astre C, Grenier J, Simony-Lafontaine J, Gerber M. Oxidant-antioxidant status in relation to survival among breast cancer patients. International Journal of Cancer. 2002;97(5):574–579. 
  6. Willett WC, Stampfer MJ. What vitamins should I be taking, doctor? The New England Journal of Medicine. 2001;345(25):1819–1824.
  7. Ingram D, Sanders K, Kolybaba M, Lopez D. Case-control study of phyto-oestrogens and breast cancer. The Lancet. 1997;350(9083):990–994. 
  8. Messina MJ. Legumes and soybeans: overview of their nutritional profiles and health effects. The American Journal of Clinical Nutrition. 1999;70(3, supplement):439S–450S. 
  9. Yamamoto S, Sobue T, Kobayashi M, et al. Soy, isoflavones, and breast cancer risk in Japan. Journal of the National Cancer Institute. 2003;95(12):906–913. 
  10. Chan JM, Stampfer MJ, Ma J, Rimm EB, Willett WC, Giovannucci EL. Supplemental vitamin E intake and prostate cancer risk in a large cohort of men in the United States. Cancer Epidemiology Biomarkers and Prevention. 1999;8(10):893–899. 
  11. Klein EA, Thompson IM, Jr., Tangen CM, et al. Vitamin E and the risk of prostate cancer: the selenium and vitamin E cancer prevention trial (SELECT) The Journal of the American Medical Association. 2011;306(14):1549–1556. 
  12. Syed DN, Khan N, Afaq F, Mukhtar H. Chemoprevention of prostate cancer through dietary agents: progress and promise. Cancer Epidemiology Biomarkers and Prevention. 2007;16(11):2193–2203. [PubMed] [Google Scholar]
  13. Gupta S, Hussain T, Mukhtar H. Molecular pathway for (-)-epigallocatechin-3-gallate-induced cell cycle arrest and apoptosis of human prostate carcinoma cells. Archives of Biochemistry and Biophysics. 2003;410(1):177–185. 
  14. Garbisa S, Biggin S, Cavallarin N, Sartor L, Benelli R, Albini A. Tumor invasion: molecular shears blunted by green tea. Nature Medicine. 1999;5(11):p. 1216.




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